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Inhibition of Drug‐Induced Liver Injury in Mice Using a Positively Charged Peptide That Binds DNA
Hepatic cell death occurs in response to diverse stimuli such as chemical and physical damage. The exposure of intracellular contents such as DNA during necrosis induces a severe inflammatory response that has yet to be fully explored therapeutically. Here, we sought means to neutralize the ability...
Autores principales: | Marques, Pedro E., Vandendriessche, Sofie, de Oliveira, Thiago H.C., Crijns, Helena, Lopes, Mateus E., Blanter, Marfa, Schuermans, Sara, Yu, Karen, Poosti, Fariba, Vanheule, Vincent, Janssens, Rik, Boff, Daiane, Kungl, Andreas J., Menezes, Gustavo B., Teixeira, Mauro M., Proost, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485890/ https://www.ncbi.nlm.nih.gov/pubmed/34532999 http://dx.doi.org/10.1002/hep4.1759 |
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