Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury

Drug‐induced hepatotoxicity limits development of new effective medications. Drugs and numerous endogenous/exogenous agents are metabolized/detoxified by hepatocytes, during which reactive oxygen species (ROS) are generated as a by‐product. ROS has broad adverse effects on liver function and integri...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Xiao, Zhang, Zhiguo, Shen, Hong, Xiong, Yi, Shah, Yatrik M., Liu, Yong, Fan, Xue‐Gong, Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485893/
https://www.ncbi.nlm.nih.gov/pubmed/34558831
http://dx.doi.org/10.1002/hep4.1757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485893/
https://www.ncbi.nlm.nih.gov/pubmed/34558831
http://dx.doi.org/10.1002/hep4.1757

Ejemplares similares