CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors

CalDAG-GEFI (CDGI) is a protein highly enriched in the striatum, particularly in the principal spiny projection neurons (SPNs). CDGI is strongly down-regulated in two hyperkinetic conditions related to striatal dysfunction: Huntington’s disease and levodopa-induced dyskinesia in Parkinson’s disease....

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Detalles Bibliográficos
Autores principales: Crittenden, Jill R., Zhai, Shenyu, Sauvage, Magdalena, Kitsukawa, Takashi, Burguière, Eric, Thomsen, Morgane, Zhang, Hui, Costa, Cinzia, Martella, Giuseppina, Ghiglieri, Veronica, Picconi, Barbara, Pescatore, Karen A., Unterwald, Ellen M., Jackson, Walker S., Housman, David E., Caine, S. Barak, Sulzer, David, Calabresi, Paolo, Smith, Anne C., Surmeier, D. James, Graybiel, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486000/
https://www.ncbi.nlm.nih.gov/pubmed/34371144
http://dx.doi.org/10.1016/j.nbd.2021.105473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486000/
https://www.ncbi.nlm.nih.gov/pubmed/34371144
http://dx.doi.org/10.1016/j.nbd.2021.105473

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