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Sequencing DNA with nanopores: Troubles and biases

Oxford Nanopore Technologies’ (ONT) long read sequencers offer access to longer DNA fragments than previous sequencer generations, at the cost of a higher error rate. While many papers have studied read correction methods, few have addressed the detailed characterization of observed errors, a task c...

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Detalles Bibliográficos
Autores principales: Delahaye, Clara, Nicolas, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486125/
https://www.ncbi.nlm.nih.gov/pubmed/34597327
http://dx.doi.org/10.1371/journal.pone.0257521