Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon

Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462) conducted in Gabon. Here, we characterized T cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Mouwenda, Yoanne D., Betouke Ongwe, Madeleine E., Sonnet, Friederike, Stam, Koen A., Labuda, Lucja A., De Vries, Sophie, Grobusch, Martin P., Zinsou, Frejus J., Honkpehedji, Yabo J., Dejon Agobe, Jean-Claude, Diemert, David J., van Leeuwen, Remko, Bottazzi, Maria E., Hotez, Peter J., Kremsner, Peter G., Bethony, Jeffrey M., Jochems, Simon P., Adegnika, Ayola A., Massinga Loembe, Marguerite, Yazdanbakhsh, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486127/
https://www.ncbi.nlm.nih.gov/pubmed/34597297
http://dx.doi.org/10.1371/journal.pntd.0009732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486127/
https://www.ncbi.nlm.nih.gov/pubmed/34597297
http://dx.doi.org/10.1371/journal.pntd.0009732

Ejemplares similares