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A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are matters of concern for public health. Thioridazine, a compound belonging to the phenothiazine group, has previous shown antimicrobial...

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Detalles Bibliográficos
Autores principales: Ronco, Troels, Aragao, Francisca Maria, Saaby, Lasse, Christensen, Jørn B., Permin, Anders, Williams, Andrew R., Thamsborg, Stig M., Olsen, Rikke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486139/
https://www.ncbi.nlm.nih.gov/pubmed/34597343
http://dx.doi.org/10.1371/journal.pone.0258207