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SCN2A contributes to oligodendroglia excitability and development in the mammalian brain

Spiking immature oligodendrocytes (OLs), referred to as spiking OLs, express voltage-activated Na(+) channels (Na(v)) and K(+) (K(v)) channels, endowing a subpopulation of OLs with the ability to generate Na(v)-driven spikes. In this study, we investigate the molecular profile of spiking OLs, using...

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Detalles Bibliográficos
Autores principales: Gould, Elizabeth, Kim, Jun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486143/
https://www.ncbi.nlm.nih.gov/pubmed/34496232
http://dx.doi.org/10.1016/j.celrep.2021.109653