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Leukemogenesis via aberrant self‐renewal by the MLL/AEP‐mediated transcriptional activation system
Homeostasis of the hematopoietic system is achieved in a hierarchy, with hematopoietic stem cells at the pinnacle. Because only hematopoietic stem cells (HSCs) can self‐renew, the size of the hematopoietic system is strictly controlled. In hematopoietic reconstitution experiments, 1 HSC can reconsti...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486200/ https://www.ncbi.nlm.nih.gov/pubmed/34251718 http://dx.doi.org/10.1111/cas.15054 |