Evi1 upregulates Fbp1 and supports progression of acute myeloid leukemia through pentose phosphate pathway activation

Evi1 is a transcription factor essential for the development as well as progression of acute myeloid leukemia (AML) and high Evi1 AML is associated with extremely poor clinical outcome. Since targeting metabolic vulnerability is the emerging therapeutic strategy of cancer, we herein investigated a n...

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Detalles Bibliográficos
Autores principales: Mizuno, Hideaki, Koya, Junji, Masamoto, Yosuke, Kagoya, Yuki, Kurokawa, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486204/
https://www.ncbi.nlm.nih.gov/pubmed/34363719
http://dx.doi.org/10.1111/cas.15098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486204/
https://www.ncbi.nlm.nih.gov/pubmed/34363719
http://dx.doi.org/10.1111/cas.15098

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