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The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3‐PHB2 complex formation

Previous studies reported the critical role of the brefeldin A–inhibited guanine nucleotide exchange protein 3–prohibitin 2 (BIG3‐PHB2) complex in modulating estrogen signaling activation in breast cancer cells, yet its pathophysiological roles in osteosarcoma (OS) cells remain elusive. Here, we rep...

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Detalles Bibliográficos
Autores principales: Toki, Shunichi, Yoshimaru, Tetsuro, Matsushita, Yosuke, Aihara, Hitoshi, Ono, Masaya, Tsuneyama, Koichi, Sairyo, Koichi, Katagiri, Toyomasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486206/
https://www.ncbi.nlm.nih.gov/pubmed/34363714
http://dx.doi.org/10.1111/cas.15099