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Loss of Krüppel‐like factor 9 facilitates stemness in ovarian cancer ascites‐derived multicellular spheroids via Notch1/slug signaling

The ascites that develops in advanced OC, both at diagnosis and upon recurrence, is a rich source of multicellular spheroids/aggregates (MCSs/MCAs), which are the major seeds of tumor cell dissemination within the abdominal cavity. However, the molecular mechanism by which specific ascites‐derived t...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Liu, Shujie, Dou, Zhiyuan, Zhang, Shuo, Yang, Xingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486214/
https://www.ncbi.nlm.nih.gov/pubmed/34363722
http://dx.doi.org/10.1111/cas.15100