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Preclinical development of plant‐based oral immune modulatory therapy for haemophilia B

Anti‐drug antibody (ADA) formation is a major complication in treatment of the X‐linked bleeding disorder haemophilia B (deficiency in coagulation factor IX, FIX). Current clinical immune tolerance protocols are often not effective due to complications such as anaphylactic reactions against FIX. Pla...

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Detalles Bibliográficos
Autores principales: Srinivasan, Aparajitha, Herzog, Roland W., Khan, Imran, Sherman, Alexandra, Bertolini, Thais, Wynn, Tung, Daniell, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486253/
https://www.ncbi.nlm.nih.gov/pubmed/33949086
http://dx.doi.org/10.1111/pbi.13608