Cargando…
Preclinical development of plant‐based oral immune modulatory therapy for haemophilia B
Anti‐drug antibody (ADA) formation is a major complication in treatment of the X‐linked bleeding disorder haemophilia B (deficiency in coagulation factor IX, FIX). Current clinical immune tolerance protocols are often not effective due to complications such as anaphylactic reactions against FIX. Pla...
Autores principales: | Srinivasan, Aparajitha, Herzog, Roland W., Khan, Imran, Sherman, Alexandra, Bertolini, Thais, Wynn, Tung, Daniell, Henry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486253/ https://www.ncbi.nlm.nih.gov/pubmed/33949086 http://dx.doi.org/10.1111/pbi.13608 |
Ejemplares similares
-
Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice
por: Kwon, Kwang‐Chul, et al.
Publicado: (2017) -
Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia
por: Kumar, Sandeep R. P., et al.
Publicado: (2020) -
Plant cell-made protein antigens for induction of Oral tolerance
por: Daniell, Henry, et al.
Publicado: (2019) -
Distinct functions and transcriptional signatures in orally induced regulatory T cell populations
por: Biswas, Moanaro, et al.
Publicado: (2023) -
Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells
por: Kwon, Kwang-Chul, et al.
Publicado: (2016)