Novel 1′-homo-N-2′-deoxy-α-nucleosides: synthesis, characterization and biological activity

For the first time, a series of novel 1′-homo-N-2′-deoxy-α-nucleosides containing natural nucleobases as well as 5-fluoro and 5-iodopyrimidine analogs have been synthesized in an efficient manner. Additionally, a high yield protocol for the assembly of a dimeric scaffold containing two sugar moietie...

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Detalles Bibliográficos
Autores principales: Carnero, Alejandro, Martín-Nieves, Virginia, Sanghvi, Yogesh S., Russel, Olivia O., Bassit, Leda, Schinazi, Raymond F., Fernández, Susana, Ferrero, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486263/
https://www.ncbi.nlm.nih.gov/pubmed/34603689
http://dx.doi.org/10.1039/d0ra03254a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486263/
https://www.ncbi.nlm.nih.gov/pubmed/34603689
http://dx.doi.org/10.1039/d0ra03254a

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