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Novel 1′-homo-N-2′-deoxy-α-nucleosides: synthesis, characterization and biological activity
For the first time, a series of novel 1′-homo-N-2′-deoxy-α-nucleosides containing natural nucleobases as well as 5-fluoro and 5-iodopyrimidine analogs have been synthesized in an efficient manner. Additionally, a high yield protocol for the assembly of a dimeric scaffold containing two sugar moietie...
Autores principales: | Carnero, Alejandro, Martín-Nieves, Virginia, Sanghvi, Yogesh S., Russel, Olivia O., Bassit, Leda, Schinazi, Raymond F., Fernández, Susana, Ferrero, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486263/ https://www.ncbi.nlm.nih.gov/pubmed/34603689 http://dx.doi.org/10.1039/d0ra03254a |
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