Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer

METHODS: In this study, qRT-PCR was used to investigate the expression levels of the SOX15 gene and of miR-182, miR-183, miR-375, and miR-96 in thyroid tumors and adjacent noncancerous tissues. We also investigated the methylation status of the SOX15 promoter by methylation-specific PCR in tumors an...

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Detalles Bibliográficos
Autores principales: Ozaydin, Ahmet, Soysal, Aysegul, Seyhan, Betul, Arikan, Soykan, Dalay, Nejat, Buyru, Nur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486500/
https://www.ncbi.nlm.nih.gov/pubmed/34603557
http://dx.doi.org/10.1155/2021/1588220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486500/
https://www.ncbi.nlm.nih.gov/pubmed/34603557
http://dx.doi.org/10.1155/2021/1588220

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