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Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer
METHODS: In this study, qRT-PCR was used to investigate the expression levels of the SOX15 gene and of miR-182, miR-183, miR-375, and miR-96 in thyroid tumors and adjacent noncancerous tissues. We also investigated the methylation status of the SOX15 promoter by methylation-specific PCR in tumors an...
Autores principales: | Ozaydin, Ahmet, Soysal, Aysegul, Seyhan, Betul, Arikan, Soykan, Dalay, Nejat, Buyru, Nur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486500/ https://www.ncbi.nlm.nih.gov/pubmed/34603557 http://dx.doi.org/10.1155/2021/1588220 |
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