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SIRT5-Related Desuccinylation Modification Contributes to Quercetin-Induced Protection against Heart Failure and High-Glucose-Prompted Cardiomyocytes Injured through Regulation of Mitochondrial Quality Surveillance

Myocardial fibrosis represents the primary pathological change associated with diabetic cardiomyopathy and heart failure, and it leads to decreased myocardial compliance with impaired cardiac diastolic and systolic function. Quercetin, an active ingredient in various medicinal plants, exerts therape...

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Detalles Bibliográficos
Autores principales: Chang, Xing, Zhang, Tian, Wang, Junyan, Liu, Yan, Yan, Peizheng, Meng, Qingyan, Yin, Yongtian, Wang, Shiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486530/
https://www.ncbi.nlm.nih.gov/pubmed/34603599
http://dx.doi.org/10.1155/2021/5876841