VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

Histone modification is aberrantly regulated in cancer and generates an unbalanced state of gene transcription. VprBP, a recently identified kinase, phosphorylates histone H2A on threonine 120 (T120) and is involved in oncogenic transcriptional dysregulation; however, its specific role in colon canc...

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Detalles Bibliográficos
Autores principales: Ghate, Nikhil Baban, Kim, Sangnam, Spiller, Erin, Kim, Sungmin, Shin, Yonghwan, Rhie, Suhn K., Smbatyan, Goar, Lenz, Heinz‐Josef, Mumenthaler, Shannon M., An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486565/
https://www.ncbi.nlm.nih.gov/pubmed/34312968
http://dx.doi.org/10.1002/1878-0261.13068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486565/
https://www.ncbi.nlm.nih.gov/pubmed/34312968
http://dx.doi.org/10.1002/1878-0261.13068

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