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Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis

PURPOSE: Congenital hypothyroidism (CH) is a common congenital endocrine disorder in humans. CH-related diseases such as athyreosis, thyroid ectopy, and hypoplasia are primarily caused by dysgenic thyroid development. However, the underlying molecular mechanisms remain unknown. METHODS: To identify...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Meng, Zhan, Ming, Zhou, Qin-Yi, Ye, Xiao-Ping, Wu, Feng-Yao, Dong, Mei, Sun, Feng, Fang, Ya, Zhang, Rui-Jia, Zhang, Chang-Run, Yang, Liu, Guo, Miao-Miao, Zhang, Jun-Xiu, Liang, Jun, Cheng, Feng, Liu, Wei, Han, Bing, Zhou, Yi, Zhao, Shuang-Xia, Song, Huai-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486662/
https://www.ncbi.nlm.nih.gov/pubmed/34194003
http://dx.doi.org/10.1038/s41436-021-01237-3