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Removal of CD276(+) cells from haploidentical memory T-cell grafts significantly lowers the risk of GVHD
Detrimental graft-versus-host disease (GVHD) still remains a major cause of death in hematopoietic stem cell transplantation (HSCT). The recently explored depletion of naive cells from mobilized grafts (CD45RA depletion) has shown considerable promise, yet is unable to eliminate the incidence of GVH...
Autores principales: | Hashimoto, Hisayoshi, Kasteleiner, Patrick, Kressin, Jakob, Müller, Friederike, Bühring, Hans-Jörg, Handgretinger, Rupert, Schilbach, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486669/ https://www.ncbi.nlm.nih.gov/pubmed/33976380 http://dx.doi.org/10.1038/s41409-021-01307-9 |
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