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Soft surfaces promote astrocytic differentiation of mouse embryonic neural stem cells via dephosphorylation of MRLC in the absence of serum

Astrocytes, which can be obtained from neural stem cells (NSCs) by adding serum and/or recombinant proteins in culture media or by passaging NSCs repeatedly, are expected to be applicable in regenerative medicine for the treatment of neurodegenerative diseases. However, astrocytes obtained using exi...

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Detalles Bibliográficos
Autores principales: Oyama, Hiroshi, Nukuda, Akihiro, Ishihara, Seiichiro, Haga, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486742/
https://www.ncbi.nlm.nih.gov/pubmed/34599241
http://dx.doi.org/10.1038/s41598-021-99059-5