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Soft surfaces promote astrocytic differentiation of mouse embryonic neural stem cells via dephosphorylation of MRLC in the absence of serum
Astrocytes, which can be obtained from neural stem cells (NSCs) by adding serum and/or recombinant proteins in culture media or by passaging NSCs repeatedly, are expected to be applicable in regenerative medicine for the treatment of neurodegenerative diseases. However, astrocytes obtained using exi...
Autores principales: | Oyama, Hiroshi, Nukuda, Akihiro, Ishihara, Seiichiro, Haga, Hisashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486742/ https://www.ncbi.nlm.nih.gov/pubmed/34599241 http://dx.doi.org/10.1038/s41598-021-99059-5 |
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