BRCA1 prevents R-loop-associated centromeric instability

Centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive α-satellite sequences, which are actively transcribed throughout the cell cycle. Centromeres play an essential role in chromosome inheritance and genome stability through coordinating kinetochores...

Descripción completa

Detalles Bibliográficos
Autores principales: Racca, Carine, Britton, Sébastien, Hédouin, Sabrine, Francastel, Claire, Calsou, Patrick, Larminat, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486751/
https://www.ncbi.nlm.nih.gov/pubmed/34599155
http://dx.doi.org/10.1038/s41419-021-04189-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486751/
https://www.ncbi.nlm.nih.gov/pubmed/34599155
http://dx.doi.org/10.1038/s41419-021-04189-3

Ejemplares similares