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BRCA1 prevents R-loop-associated centromeric instability

Centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive α-satellite sequences, which are actively transcribed throughout the cell cycle. Centromeres play an essential role in chromosome inheritance and genome stability through coordinating kinetochores...

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Detalles Bibliográficos
Autores principales:	Racca, Carine, Britton, Sébastien, Hédouin, Sabrine, Francastel, Claire, Calsou, Patrick, Larminat, Florence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486751/ https://www.ncbi.nlm.nih.gov/pubmed/34599155 http://dx.doi.org/10.1038/s41419-021-04189-3

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