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CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells

Regulatory T (Treg) cells are one of the major immunosuppressive cell types in cancer and a potential target for immunotherapy, but targeting tumor-infiltrating (TI) Treg cells has been challenging. Here, using single-cell RNA sequencing of immune cells from renal clear cell carcinoma (ccRCC) patien...

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Detalles Bibliográficos
Autores principales: Kim, Myung-Chul, Borcherding, Nicholas, Ahmed, Kawther K., Voigt, Andrew P., Vishwakarma, Ajaykumar, Kolb, Ryan, Kluz, Paige N., Pandey, Gaurav, De, Umasankar, Drashansky, Theodore, Helm, Eric Y., Zhang, Xin, Gibson-Corley, Katherine N., Klesney-Tait, Julia, Zhu, Yuwen, Lu, Jinglu, Lu, Jinsong, Huang, Xian, Xiang, Hongrui, Cheng, Jinke, Wang, Dongyang, Wang, Zheng, Tang, Jian, Hu, Jiajia, Wang, Zhengting, Liu, Hua, Li, Mingjia, Zhuang, Haoyang, Avram, Dorina, Zhou, Daohong, Bacher, Rhonda, Zheng, Song Guo, Wu, Xuefeng, Zakharia, Yousef, Zhang, Weizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486774/
https://www.ncbi.nlm.nih.gov/pubmed/34599187
http://dx.doi.org/10.1038/s41467-021-26091-4