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Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling
Glioblastoma (GBM) is a prevalent and highly lethal form of glioma, with rapid tumor progression and frequent recurrence. Excessive outgrowth of pericytes in GBM governs the ecology of the perivascular niche, but their function in mediating chemoresistance has not been fully explored. Herein, we unc...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486800/ https://www.ncbi.nlm.nih.gov/pubmed/34239070 http://dx.doi.org/10.1038/s41422-021-00528-3 |