Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling

Glioblastoma (GBM) is a prevalent and highly lethal form of glioma, with rapid tumor progression and frequent recurrence. Excessive outgrowth of pericytes in GBM governs the ecology of the perivascular niche, but their function in mediating chemoresistance has not been fully explored. Herein, we unc...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Ning, Yang, Kai-Di, Chen, Cong, He, Zhi-Cheng, Wang, Qiang-Hu, Feng, Hua, Lv, Sheng-Qing, Wang, Yan, Mao, Min, Liu, Qing, Tan, Yao-Yao, Wang, Wen-Ying, Li, Tian-Ran, Che, Lin-Rong, Qin, Zhong-Yi, Wu, Ling-Xiang, Luo, Min, Luo, Chun-Hua, Liu, Yu-Qi, Yin, Wen, Wang, Chao, Guo, Hai-Tao, Li, Qing-Rui, Wang, Bin, Chen, Wei, Wang, Shuang, Shi, Yu, Bian, Xiu-Wu, Ping, Yi-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486800/
https://www.ncbi.nlm.nih.gov/pubmed/34239070
http://dx.doi.org/10.1038/s41422-021-00528-3

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