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Intrathymic differentiation of natural antibody-producing plasma cells in human neonates

The thymus is a central lymphoid organ primarily responsible for the development of T cells. A small proportion of B cells, however, also reside in the thymus to assist negative selection of self-reactive T cells. Here we show that the thymus of human neonates contains a consistent contingent of CD1...

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Detalles Bibliográficos
Autores principales: Cordero, Hector, King, Rodney G., Dogra, Pranay, Dufeu, Chloe, See, Sarah B., Chong, Alexander M., Uhlemann, Anne-Catrin, Ho, Siu-Hong, Kalfa, David M., Bacha, Emile A., Kearney, John F., Zorn, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486820/
https://www.ncbi.nlm.nih.gov/pubmed/34599177
http://dx.doi.org/10.1038/s41467-021-26069-2