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Exome-wide association study of levodopa-induced dyskinesia in Parkinson’s disease

Levodopa is the standard long-term dopamine replacement therapy to treat Parkinson’s disease (PD) symptoms. With time, levodopa may induce debilitating dyskinesias (LID), the treatment of which represents a large clinically unmet need. However, time-to-LID onset varies between patients, reflecting a...

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Detalles Bibliográficos
Autores principales: König, Eva, Nicoletti, Alessandra, Pattaro, Cristian, Annesi, Grazia, Melotti, Roberto, Gialluisi, Alessandro, Schwienbacher, Christine, Picard, Anne, Blankenburg, Hagen, Pichler, Irene, Modugno, Nicola, Ciullo, Marina, Esposito, Teresa, Domingues, Francisco S., Hicks, Andrew A., Zappia, Mario, Pramstaller, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486836/
https://www.ncbi.nlm.nih.gov/pubmed/34599261
http://dx.doi.org/10.1038/s41598-021-99393-8