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Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney

Increasing evidence suggests that single in kidney states (e.g., kidney transplantation and living donation) progressive glomerulosclerosis limits kidney lifespan. Modeling shows that post-nephrectomy compensatory glomerular volume (GV) increase drives podocyte depletion and hypertrophic stress resu...

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Detalles Bibliográficos
Autores principales: Naik, Abhijit S., Wang, Su Q., Chowdhury, Mahboob, Aqeel, Jawad, O’Connor, Christopher L., Wiggins, Jocelyn E., Bitzer, Markus, Wiggins, Roger C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486841/
https://www.ncbi.nlm.nih.gov/pubmed/34599260
http://dx.doi.org/10.1038/s41598-021-99124-z