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Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney
Increasing evidence suggests that single in kidney states (e.g., kidney transplantation and living donation) progressive glomerulosclerosis limits kidney lifespan. Modeling shows that post-nephrectomy compensatory glomerular volume (GV) increase drives podocyte depletion and hypertrophic stress resu...
Autores principales: | Naik, Abhijit S., Wang, Su Q., Chowdhury, Mahboob, Aqeel, Jawad, O’Connor, Christopher L., Wiggins, Jocelyn E., Bitzer, Markus, Wiggins, Roger C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486841/ https://www.ncbi.nlm.nih.gov/pubmed/34599260 http://dx.doi.org/10.1038/s41598-021-99124-z |
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