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A vascularized tumoroid model for human glioblastoma angiogenesis

Glioblastoma (GBM) angiogenesis is critical for tumor growth and recurrence, making it a compelling therapeutic target. Here, a disease-relevant, vascularized tumoroid in vitro model with stem-like features and stromal surrounds is reported. The model is used to recapitulate how individual component...

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Detalles Bibliográficos
Autores principales: Tatla, Agavi Stavropoulou, Justin, Alexander W., Watts, Colin, Markaki, Athina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486855/
https://www.ncbi.nlm.nih.gov/pubmed/34599235
http://dx.doi.org/10.1038/s41598-021-98911-y