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Pioneer factors in development and cancer

Transcription factors (TFs) are essential mediators of epigenetic regulation and modifiers of penetrance. Studies from the past decades have revealed a sub-class of TF that is capable of remodeling closed chromatin states through targeting nucleosomal motifs. This pioneer factor (PF) class of chroma...

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Detalles Bibliográficos
Autores principales: Sunkel, Benjamin D., Stanton, Benjamin Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487031/
https://www.ncbi.nlm.nih.gov/pubmed/34632331
http://dx.doi.org/10.1016/j.isci.2021.103132