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Multiplatform metabolomic analysis of the R6/2 mouse model of Huntington’s disease

Huntington’s disease (HD) is a progressive, neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. To investigate the metabolic alterations that occur in HD, here we examined plasma and whole‐brain metabolomic profiles of the R6/2 mouse model of HD. Plasma and brain m...

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Detalles Bibliográficos
Autores principales: Hashimoto, Masayo, Watanabe, Kenichi, Miyoshi, Kan, Koyanagi, Yukako, Tadano, Jun, Miyawaki, Izuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487039/
https://www.ncbi.nlm.nih.gov/pubmed/34469070
http://dx.doi.org/10.1002/2211-5463.13285