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MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway

Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a bifunctional enzyme located in the mitochondria. MTHFD2 has been reported to be overexpressed in several malignant tumors and is implicated in cancer development. This study aimed to investigate the effect of MTHFD2 on ovarian cancer progressio...

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Detalles Bibliográficos
Autores principales: Li, Qiutong, Yang, Fang, Shi, Xiu, Bian, Shimin, Shen, Fangrong, Wu, Yuhong, Zhu, Chenjie, Fu, Fengqing, Wang, Juan, Zhou, Jinhua, Chen, Youguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487042/
https://www.ncbi.nlm.nih.gov/pubmed/34231329
http://dx.doi.org/10.1002/2211-5463.13249