Melatonin binds with high affinity and specificity to beta‐amyloid: LC‐MS provides insight into Alzheimer’s disease treatment

To study the potential relationship between melatonin and beta‐amyloid (Abeta), we established a liquid chromatography–mass spectrometry (LC‐MS) method to quantitatively analyze melatonin, deuterated isotopes (melatonin‐D4), and internal standard 6‐iodo‐2‐(4'‐dimethylamino‐) phenyl‐imidazo(1,2)...

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Detalles Bibliográficos
Autores principales: Dai, Yaqian, Peng, Liduo, Liu, Yajing, Xu, Yuanhong, Qiao, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487044/
https://www.ncbi.nlm.nih.gov/pubmed/34428352
http://dx.doi.org/10.1002/2211-5463.13279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487044/
https://www.ncbi.nlm.nih.gov/pubmed/34428352
http://dx.doi.org/10.1002/2211-5463.13279

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