Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR–p70S6K pathway

Cell senescence is closely related to autophagy. In this article, we identified a natural nucleoside analogue, cordycepin, that has the ability to significantly improve lysosomal function, enhance the activity of the lysosomal representative protease cathepsin B (CTSB), and promote the expression of...

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Detalles Bibliográficos
Autores principales: Zuo, Shi Qi, Li, Can, Liu, Yi Lun, Tan, Yue Hao, Wan, Xing, Xu, Tian, Li, Qiang, Wang, Li, Wu, Yong Li, Deng, Feng Mei, Tang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487049/
https://www.ncbi.nlm.nih.gov/pubmed/34448542
http://dx.doi.org/10.1002/2211-5463.13263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487049/
https://www.ncbi.nlm.nih.gov/pubmed/34448542
http://dx.doi.org/10.1002/2211-5463.13263

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