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Zfhx3-mediated genetic ablation of the SCN abolishes light entrainable circadian activity while sparing food anticipatory activity

Circadian rhythms persist in almost all organisms and are crucial for maintaining appropriate timing in physiology and behaviour. Here, we describe a mouse mutant where the central mammalian pacemaker, the suprachiasmatic nucleus (SCN), has been genetically ablated by conditional deletion of the tra...

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Detalles Bibliográficos
Autores principales: Wilcox, Ashleigh G., Bains, R. Sonia, Williams, Debbie, Joynson, Elizabeth, Vizor, Lucie, Oliver, Peter L., Maywood, Elizabeth S., Hastings, Michael H., Banks, Gareth, Nolan, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487057/
https://www.ncbi.nlm.nih.gov/pubmed/34632336
http://dx.doi.org/10.1016/j.isci.2021.103142