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ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium

Very low-density lipoprotein receptor (VLDLR) is a multifunctional transmembrane protein. Beyond the function of the full-length VLDLR in lipid transport, the soluble ectodomain of VLDLR (sVLDLR) confers anti-inflammatory and antiangiogenic roles in ocular tissues through inhibition of canonical Wnt...

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Detalles Bibliográficos
Autores principales: Ma, Xiang, Takahashi, Yusuke, Wu, Wenjing, Liang, Wentao, Chen, Jianglei, Chakraborty, Dibyendu, Li, Yangxiong, Du, Yanhong, Benyajati, Siribhinya, Ma, Jian-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487060/
https://www.ncbi.nlm.nih.gov/pubmed/34509473
http://dx.doi.org/10.1016/j.jbc.2021.101185