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Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro

Long-terminal repeat (LTR) retrotransposons are genetic elements that, like retroviruses, replicate by reverse transcription of an RNA intermediate into a complementary DNA (cDNA) that is next integrated into the host genome by their own integrase. The Ty1 LTR retrotransposon has proven to be a reli...

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Detalles Bibliográficos
Autores principales: Nguyen, Phong Quoc, Conesa, Christine, Rabut, Elise, Bragagnolo, Gabriel, Gouzerh, Célia, Fernández-Tornero, Carlos, Lesage, Pascale, Reguera, Juan, Acker, Joël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487063/
https://www.ncbi.nlm.nih.gov/pubmed/34416236
http://dx.doi.org/10.1016/j.jbc.2021.101093