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Titratable transmembrane residues and a hydrophobic plug are essential for manganese import via the Bacillus anthracis ABC transporter MntBC-A

All extant life forms require trace transition metals (e.g., Fe(2/3+), Cu(1/2+), and Mn(2+)) to survive. However, as these are environmentally scarce, organisms have evolved sophisticated metal uptake machineries. In bacteria, high-affinity import of transition metals is predominantly mediated by AB...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Anastasiya, Masrati, Gal, Vigonsky, Elena, Livnat-Levanon, Nurit, Rose, Jessica, Grupper, Moti, Baloum, Adan, Yang, Janet G., Rees, Douglas C., Ben-Tal, Nir, Lewinson, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487065/
https://www.ncbi.nlm.nih.gov/pubmed/34416234
http://dx.doi.org/10.1016/j.jbc.2021.101087