The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress

The deubiquitinating enzyme USP37 is known to contribute to timely onset of S phase and progression of mitosis. However, it is not clear if USP37 is required beyond S-phase entry despite expression and activity of USP37 peaking within S phase. We have utilized flow cytometry and microscopy to analyz...

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Detalles Bibliográficos
Autores principales: Stromberg, Benjamin R., Singh, Mayank, Torres, Adrian E., Burrows, Amy C., Pal, Debjani, Insinna, Christine, Rhee, Yosup, Dickson, Andrew S., Westlake, Christopher J., Summers, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487067/
https://www.ncbi.nlm.nih.gov/pubmed/34509474
http://dx.doi.org/10.1016/j.jbc.2021.101184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487067/
https://www.ncbi.nlm.nih.gov/pubmed/34509474
http://dx.doi.org/10.1016/j.jbc.2021.101184

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