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Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

To determine the roles of nuclear localization of pro-caspase-1 in human aortic endothelial cells (HAECs) activated by proatherogenic lipid lysophosphatidylcholine (LPC), we examined cytosolic and nuclear localization of pro-caspase-1, identified nuclear export signal (NES) in pro-caspase-1 and sequ...

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Detalles Bibliográficos
Autores principales: Lu, Yifan, Nanayakkara, Gayani, Sun, Yu, Liu, Lu, Xu, Keman, Drummer, Charles, Shao, Ying, Saaoud, Fatma, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487079/
https://www.ncbi.nlm.nih.gov/pubmed/34598017
http://dx.doi.org/10.1016/j.redox.2021.102142