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Comprehensive characterization and clinical relevance of the SWI/SNF copy number aberrations across human cancers

BACKGROUND: Alterations in genes encoding chromatin regulatory proteins are prevalent in cancers and may confer oncogenic properties and molecular changes linked to therapy resistance. However, the impact of copy number alterations (CNAs) of the SWItch/Sucrose NonFermentable (SWI/SNF) complex on the...

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Detalles Bibliográficos
Autores principales: Xing, Zhiwei, Ma, Buhuan, Sun, Weiting, Sun, Yimin, Liu, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487138/
https://www.ncbi.nlm.nih.gov/pubmed/34598711
http://dx.doi.org/10.1186/s41065-021-00203-y