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Suppressor of variegation 3–9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD

BACKGROUND: Systemic manifestations and comorbidities are characteristics of chronic obstructive pulmonary disease (COPD) and are probably due to systemic inflammation. The histone methyltransferase SUV39H1 controls the Th1/Th2 balance. We previously reported that reduced SUV39H1 expression contribu...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Tao, Wu, Sheng-Ming, Chen, Kuan-Yuan, Tseng, Chien-Hua, Ho, Shu-Chuan, Chuang, Hsiao-Chi, Feng, Po-Hao, Liu, Wen-Te, Han, Chia-Li, Huang, Erick Wan-Chun, Yeh, Yun-Kai, Lee, Kang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487160/
https://www.ncbi.nlm.nih.gov/pubmed/34598691
http://dx.doi.org/10.1186/s12890-021-01628-x