CD8(+) TILs in NSCLC differentiate into TEMRA via a bifurcated trajectory: deciphering immunogenicity of tumor antigens

BACKGROUND: CD8(+) tumor-infiltrating lymphocytes (TILs) comprise phenotypically and functionally heterogeneous subpopulations. Of these, effector memory CD45RA re-expressing CD8(+) T cells (Temra) have been discovered and characterized as the most terminally differentiated subset. However, their ex...

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Detalles Bibliográficos
Autores principales: Lee, Sung-Woo, Choi, He Yun, Lee, Gil-Woo, Kim, Therasa, Cho, Hyun-Ju, Oh, In-Jae, Song, Sang Yun, Yang, Deok Hwan, Cho, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487216/
https://www.ncbi.nlm.nih.gov/pubmed/34593620
http://dx.doi.org/10.1136/jitc-2021-002709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487216/
https://www.ncbi.nlm.nih.gov/pubmed/34593620
http://dx.doi.org/10.1136/jitc-2021-002709

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