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κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca(2+)/CaMKII/CREB Pathway

OBJECTIVE: Cardiopulmonary bypass (CPB) is an important cardiac operation and also a high-risk procedure, leading to postoperative neurocognitive disorder. However, there are few effective drugs to treat the aftermath of CPB. Therefore, we observe the effect of kappa opioid receptor (KOR) agonist on...

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Detalles Bibliográficos
Autores principales: Ding, Guopeng, Li, Dandan, Sun, Yingjie, Chen, Keyan, Song, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487382/
https://www.ncbi.nlm.nih.gov/pubmed/34608407
http://dx.doi.org/10.1155/2021/3401654