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Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q

Recent studies have identified roles for complement in synaptic pruning, both physiological during development and pathological in Alzheimer’s disease (AD). These reports suggest that C1q initiates complement activation on synapses and C3 fragments then tag them for removal by microglia. There is an...

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Detalles Bibliográficos
Autores principales: Byrne, Robert A. J., Torvell, Megan, Daskoulidou, Nikoleta, Fathalla, Dina, Kokkali, Eirini, Carpanini, Sarah M., Morgan, B. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487419/
https://www.ncbi.nlm.nih.gov/pubmed/34002346
http://dx.doi.org/10.1007/s12035-021-02419-5