Cargando…

miR-539 activates the SAPK/JNK signaling pathway to promote ferropotosis in colorectal cancer by directly targeting TIPE

Colorectal cancer (CRC) is a common tumor that harms human health with a high recurrence rate. It has been reported that the expression of microRNA-539 (miR-539) is low in several types of cancer, including CRC. Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8/TIPE) is highly expressed in CR...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yan, Lin, Zeyang, Han, Zhaopu, Wu, Zhengxin, Hua, Jianyu, Zhong, Rui, Zhao, Ruidan, Ran, Honggang, Qu, Kaiyong, Huang, Hongfei, Tang, Huamei, Huang, Jiyi, Liu, Zhongchen, Hong, Xuehui, Peng, Zhihai, Zhuang, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487425/
https://www.ncbi.nlm.nih.gov/pubmed/34601499
http://dx.doi.org/10.1038/s41420-021-00659-x